Analysis and Purification Methods in Combinatorial Chemistry by Bing Yan

By Bing Yan

Caliber size, keep an eye on, and development in combinatorial chemistry Combinatorial chemistry has built speedily some time past decade, with nice advances made through scientists engaged on research and purification of a big variety of compounds and the research of polymer-bound compounds. notwithstanding, ambitious demanding situations lie prior to trendy researcher. for instance, high-throughput research and purification applied sciences needs to be additional built to make sure combinatorial libraries are "purifiable," and "drugable."

To this finish, research and Purification equipment in Combinatorial Chemistry describes quite a few analytical strategies and structures for the improvement, validation, qc, purification, and physicochemical trying out of combinatorial libraries. a brand new quantity in Wiley's Chemical research sequence, this article has 4 components masking:

  • Various techniques to tracking reactions on sturdy aid and optimizing reactions for library synthesis
  • High-throughput analytical tools used to research the standard of libraries
  • High-throughput purification techniques
  • Analytical tools utilized in post-synthesis and post-purification stages

Drawing from the contributions of revered specialists in combinatorial chemistry, this finished publication offers assurance of functions of Nuclear Magnetic Resonance (NMR), liquid chromatography/mass spectrometry (LC/MS), Fourier remodel Infrared (FTIR), micellar electrokinetic chromatography (MEKC) applied sciences, in addition to different analytical ideas.

This eminently worthwhile quantity is a vital addition to the library of scholars and researchers learning or operating in analytical chemistry, combinatorial chemistry, medicinal chemistry, natural chemistry, biotechnology, biochemistry, or biophysics.

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