Ciba Foundation Symposium - Regulation and Mode of Action of

Content:
Chapter 1 Chairmen's starting feedback (pages 1–2): Roslind Pitt?Rivers
Chapter 2 Hypothalamus?Pituitary?Thyroid Relationships (pages 3–20): G.W. Harris and J.W. Woods
Chapter three Contribution to the law of Thyroid job (pages 21–33): R. Courrier
Chapter four The impression of the important fearful method at the regulate of Thyrothropin Secretion (pages 34–50): Monte A. Greer
Chapter five Pituitary Cytology relating to Thyrotrophic Hormone Secretion (pages 51–58): H.D. Purves and W.E. Griesbach
Chapter 6 results of Hypophysectomy on natural Iodine Formation in Rat Thyroids (pages 59–78): Alvin Taurog, Winton Tong and I.L. Chaikoff
Chapter 7 elements Influencing the Thyroidal Iodide Pump (pages 79–96): N.S. Halmi
Chapter eight The “Feed?Back” speculation of the keep watch over of Thyroid functionality (pages 97–123): okay. Brown?Grant
Chapter nine Hormone Synthesis within the Iodine?Deficient Thyroid Gland (pages 124–134): A. Querido,, okay. Schut and Janke Terpstra
Chapter 10 Enzymic facets of Thyronine Metabolism and its Iodinated Derivatives (pages 135–155): S. Lissitzky and S. Bouchilloux
Chapter eleven The Metabolism of Thyroid Hormones by way of Kidney and the organic job of the goods (pages 156–167): Henry Lardy, Kenkichi Tomita, Frank C. Larson and Edwin C. Albright
Chapter 12 at the Presence of 3:5:3??Triiodothyro?Acetic Acid and 3:3??Diiodothyronine in Rat Muscle and Kidney after management of 3:5:3??Triiodo?L?Thyronine (pages 168–181): Jean Roche, Raymond Michel and Pierre Jouan
Chapter thirteen The Distribution and Metabolism of Thyroid Hormones (pages 182–189): J. Gross, D. F. Ford, S. Symchowicz and J. H. Horton
Chapter 14 The Deiodination of Thyroid Hormones in vitro (pages 190–214): N. F. Maclagan and Doreen Reid
Chapter 15 Hepatic law of Thyroxine Metabolism (pages 215–229): A. Vannotti
Chapter sixteen Thyroid Hormones on the Peripheral Tissue point: Metabolism and Mode of motion (pages 230–252): Odette Thibault
Chapter 17 mobile activities of Thyroxine and related Compounds (pages 253–269): S.B. Barker
Chapter 18 a few Observations at the scientific results of Triiodothyroacetic Acid (pages 270–286): W.R. Trotter
Chapter 19 The impact of the Thyroid Gland Upon Immune Responses of alternative Species to Bacterial an infection (pages 287–304): D.A. lengthy

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Additional resources for Ciba Foundation Symposium - Regulation and Mode of Action of Thyroid Hormones (Colloquia on Endocrinology), Volume 10

Example text

I should be interested to hear, however, whether you think there might be a correlation between this radioactive uptake and the particular type of vascularization of the gland. Wislocki and Icing some years ago (Wislocki, G . , and King, L. S. (1036). Amer. J . , 58,421)found that the permeability of the blood vessels of both lobes of the pituitary gland, of the median eminence of the tuber cinereum and of the pineal gland to intravital dyes was greater than the vessels of the other areas of the central nervous system, and we found a correspondingly greater uptake of radioactive thyroxine in just these same tissues.

The following is our usual procedure: after the injection of radioactive iodine, a sample of blood is withdrawn and centrifuged; the radioactivity is then measured using an equal weight of red blood cells (H) and plasma (P). 10 in 24 hours, and reaches a state of equilibrium. We have observed (Courrier, 1954; Courrier, Morel, Colonge and And&, 1954) that the H/P value and the thyroid activity are closely related, as can be seen from Table I showing results of experiments on rabbits. Time after injection of iVa1311(rabbits) H/P ratio (1 mg.

Halmi: They were on a high iodine diet. Zizine: Ours were on a low iodine diet. Barker: I think a real question is raised by several papers which have appeared using a red blood cell 1311 : plasma 1311ratio. Where you have an active metabolism of 1311as in the thyroid cell, or an active uptake of radioactive hormone, as in extra-thyroidal cells, I think comparison with the plasma 1311 is legitimate. However, I wonder if this ratio is not reversed where the red cell uptake of lalImay not be a physiological mechanism a t all.

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